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Interim results of a phase I trial with a novel orally administered synthetic triterpenoid RTA 402 (CDDO-Me) in patients with solid tumors and lymphoid malignancies

Issues with the kidneys, such as holding too much urine, not being able to produce enough urine, sudden kidney failure, kidney damage and inflammation, and damage to the small tubes in kidneys, are also possible, especially if your kidneys arent working properly to begin with

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The study was published in JAMA Network Open

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In the human clinical trial, the trajectory of weight loss became apparent during this window