10.1016/j.pnpbp.2020.110228 57 SestarioC
Wilding, J.P.H., et al
Quercetin, a flavonol with antioxidant and anti-inflammatory properties, has been studied for its effects on reducing OS, inhibiting LDL oxidation and platelet aggregation, and acting as a vasodilator [135]
Induction of phase II detoxifying enzymes Many isothiocyanates are potent inducers of phase II detoxifying enzymes, including GSTs, UDP-glucuronosyl transferases (UGTs), NQO1, and glutamate cysteine ligase (GCL), that protect cells from DNA damage by carcinogens and reactive oxygen species (ROS) (25)
Synergistic Combinations: AOD-9604 can be combined with other metabolic support peptides for comprehensive optimization
For statins, that means muscle symptoms, a small excess risk of diabetes in susceptible individuals, and the practical reality that long-term adherence in primary prevention is often imperfect