Subsequently, mice with cardiomyocyte-specific (CM-specific) deletion of Glp1r also showed cardioprotective effects of liraglutide in an in vivo model of MI (22), suggesting that the cardioprotective effects of this agent are derived from actions independent of CMs and/or the GLP-1R
These usually happen during the first few weeks or when increasing your dose
It is especially this kind of adipose tissue that is believed to drive a large part of the pathological effects of excess body weight ( The reductions in ROS and systemic inflammation, in combination with improvements in the other cardiometabolic parameters, are also thought to mediate the substantiated but so far formally unconfirmed kidney-protective effects of GLP-1 RAs, which may also directly or indirectly carry a HF-related benefit, considering that CKD is a prominent risk factor for HF (von Scholten et al., 2022)
Your healthcare team can provide personalised advice based on your individual circumstances, ensuring that any decision to stop GLP-1 therapy is safe, well-planned, and supported by appropriate monitoring and alternative management strategies where needed
PlexusDx providers can temporarily reduce your injection dosea strategic pause allows your gut microbiome to rebalance before you advance to the next dose level
Some rare side effects make it into the headlines