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Effects of sodium-glucose cotransporter 2 inhibitors on 24-hour ambulatory blood pressure: a systematic review and meta-analysis

Lower-dose therapy did not fully match continued high-dose therapy, but it preserved a large amount of the benefit

Interested in finding out more about the presence and nature of proglucagon products in the human body, they developed some new antibodies for use in RIAs to detect them in the human pancreas, small intestine and plasma

Gorgojo-Martnez JJ, Mezquita-Raya P, Carretero-Gmez J, et al

The modifications made to human GLP-1 include: Amino acid substitutions that resist DPP-4 enzyme degradation Attachment of fatty acid chains (acylation) as seen in semaglutide and liraglutide Fusion with immunoglobulin fragments (as in dulaglutide) to increase molecular size These changes are designed using rational drug design principles and implemented through biotechnology

[cited 2025 Feb 1]