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showed that transforming growth factor (TGF)- type II receptor knockout in mice gave rise to prostate and gut epithelial tumors by activating c-MET through paracrine overexpression of HGF by stromal cells [96]

In addition to the OASIS 1 trial, which has already achieved its primary clinical endpoint, Novo Nordisk plans to conduct a series of related clinical studies for oral semaglutide

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