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Relevant and reproducible animal models are critical for further studies of the side effects of GCs as well as novel ligands of glucocorticoid receptor (GR), in particular, selective glucocorticoid receptor agonists (SEGRAs)
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468 In a clinical trial investigating the safety of tofacitinib, UC patients treated with tofacitinib for 16 weeks (10 mg BID) did not experience significant adverse effects
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