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Podiatrists have noted this can include a loss of soft tissue, noting a reduction in fat padding can affect the cushioning of the heels and balls of the feet, resulting in foot pain

Elevated palmitate induces chondrocyte apoptosis via endoplasmic reticulum stress (ERS), while a high-fat diet promotes the formation of advanced glycation end products (AGEs), which upregulate MMPs through the RAGE receptor (1921)

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Prescription pathway: Once your GP has established the need for ongoing B12 therapy, they can issue a repeat prescription for home use