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Wound areas were quantified using ImageJ software, and all measurements were normalized to the scale bar

Then both solutions were mixed in volume ratio 1:1

The rationale for combining them is mechanistic complementarity (different signaling pathways, both implicated in tissue repair) and clinical anecdote in the peptide-therapy community not formal head-to-head or combination-vs-monotherapy data

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Editorial Note: Any opinions, analyses, reviews, or recommendations expressed in this article are the authors alone, and have not been reviewed, approved, or otherwise endorsed by any card issuer

Furthermore, the synergetic effects of TLK117 with pirfenidone showed better therapeutic outcomes in pulmonary fibrosis mice models than by using pirfenidone alone [104]