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On the other hand, "prosthetic group" emphasizes the nature of the binding of a cofactor to a protein (tight or covalent) and, thus, refers to a structural property

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Aib mimics the structure of d-amino acids, which considerably increases resistance against protease enzymes such as DPP-IV, leading to an extended half-life of up to 5 days

Proc Natl Acad Sci U S A , 108 (27), 1111511120

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La captura de carnitina por parte del cido valproico bloquea parte de la generacin de energa de la clula, particularmente la que ocurre durante la metabolizacin heptica de las grasas