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ICYMI: This long piece explored the fact that many of the adaptations we rely on to age well are triggered only when we move toward hard effort rather than away from it

In Lillys TRIUMPH-1 study, adults with obesity or overweight and at least one weight-related condition received retatrutide or placebo

Gastrointestinal side effects such as nausea, vomiting, diarrhea, or constipation are common across GLP-1 therapies

These numbers are theoretical and should be treated as directional, not guaranteed

Early recognition and timely escalation of care are essential for preventing serious AEs

He writes at the intersection of clinical medicine, health policy, and health technology, translating complex industry dynamics into sharp, evidence-based commentary for busy clinicians