Recommendations for the peri-operative management of patients taking glucagon-like peptide-1 receptor agonists and glucose-dependent insulinotropic peptide [1] : The risk of pulmonary aspiration and mitigation strategies should be discussed with the patient using a shared decision-making approach." "Patients should continue to take glucagon-like peptide-1 receptor agonists throughout the perioperative period." "Patients and clinicians should adhere to recommended fasting guidelines." "Upper gastrointestinal symptoms alone should not be used to determine gastric content." "Regional anaesthesia should be considered as the primary anaesthetic technique, if appropriate." "Point-of-care gastric ultrasound should be considered before induction of anaesthesia to facilitate risk stratification, if appropriate." "Individualised pulmonary aspiration risk assessment should be completed, accounting for drug, patient and procedural factors." "Anaesthesia and airway management should aim to reduce the risk of pulmonary aspiration on induction of anaesthesia, during maintenance and after emergence of anaesthesia
What results to expect and when Setting realistic expectations matters
CurtisSKilpatrickRBillimoriaZCZimmermanKToliaVClarkRet alUse of dexmedetomidine and opioids in hospitalized preterm infants
Each of these structures requires different therapeutic approaches, and peptides offer targeted mechanisms that conventional treatments often lack
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