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The GPX8 gene is located on chromosome 5q11.2 and is composed of 4 exons that generate four alternatively spliced mRNAs

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Miele L, Grieco A, Armuzzi A, Candelli M, Forgione A, Gasbarrini A, Gasbarrini G (2003) Hepatic mitochondrial beta-oxidation in patients with nonalcoholic steatohepatitis assessed by 13C-octanoate breath test

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For ongoing prevention, patients should aim for gradual fibre intake (2530g daily), adequate hydration (at least 1.52 litres of fluid daily, unless advised to restrict fluids due to heart or kidney conditions), and smaller, more frequent meals to manage both conditions effectively