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Medical Conditions Requiring Caution: Individuals with heart conditions Those with liver or kidney disease People with metabolic disorders Patients with Leber's disease (affecting the optic nerve) Those with low potassium levels (hypokalemia) [12] Pregnancy and breastfeeding present special considerations for MIC B12 treatment

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Ehrn I, Halln Grufman K, Vrba M et al: Nitric oxide as a marker for evaluation of treatment effect of cyclosporine a in patients with bladder pain syndrome/interstitial cystitis type 3c