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All other data supporting the findings of this study are available within the manuscript and its supplementary files or are available from the corresponding author upon request

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The results of goodness-of-fit performance test (Additional file 1: Table S4) indicated that a log-normal model was the best one to describe the latency of liraglutide- and exenatide-related SSIBs

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Ozempic , containing the active ingredient semaglutide GLP-1 , is primarily prescribed for managing type 2 diabetes

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Genetic variation in GLP-1 receptor sensitivity (rs6923761) and GIP receptor variants (rs1800437) may explain why some patients achieve robust weight loss with lower doses while others require higher doses or experience unexpected tolerability challenges

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