There are multiple ongoing trials assessing the benefit of PEG in HE
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As with other components of the BBB, long-term exposure of astrocytes to diabetes leads to cell-specific impairment

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Because glutathione supports many important cellular processes, it forms a key part of the bodys antioxidant defence system
Czarnywojtek A, Florek E, Pietronczyk K, Sawicka-Gutaj N, Ruchala M, Ronen O, Nixon IJ, Shaha AR, Rodrigo JP, Tufano RP, Zafereo ME , Randolph GW, Ferlito A