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Duration of Study: Short-term acute studies (e.g., 24-48 hours) will naturally have a different 5-Amino-1MQ dosage profile than long-term chronic studies (e.g., 4-12 weeks)

The Phase 2 trial reference point The Phase 2 retatrutide trial (Jastreboff et al., New England Journal of Medicine 2023) enrolled 338 adults across placebo and retatrutide arms at 1, 4, 8, and 12 mg weekly

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