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10.1016/j.cmpb.2019.105073 75 LiV

Limitations reflect methodological issues such as lack of standardization, absence of comparators, or insufficient clinical validation

For most people, a Vitamin C + Glutathione serum offers the best balance of safety, effectiveness, and long-term results for pigmentation and uneven skin tone, while IV glutathione should remain a specialist-led treatment for selected cases

At wavelengths below 400 nm these spectra include contributions from added NADPH which varies with each experiment and the extent of reduction observed