This finding was later combined with research by Joel Habener and jointly published in JCI.11 The team of Jens Juul Holst at the University of Copenhagen in Denmark published a report in FEBS Letters, reaching the same conclusion in January 1987.23 In December 1987, Stephen Blooms team confirmed in a Lancet paper that GLP-1(7-36) is a human intestinal hormone that stimulates insulin production in the pancreas and lowers blood sugar.24 GLP-1, used for treating diabetes, is quickly broken down in the body, requiring high doses that can cause side effects like nausea
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McGarry JD, Brown NF
Understanding the Science: Mechanisms of Action To understand why one drug might outperform the other, we must examine how they interact with the human endocrine system
More from this author: Idelalisib plus rituximab improves progression-free survival in relapsed CLL, SSRI use during pregnancy not linked to increased risk of autism,Combo antifungal therapy most effective treatment for cryptococcal meningitis Image: CC/Wiki 2012-2014 2minutemedicine.com
Teva Pharmaceuticals, another maker of generic medicines, introduced an authorized generic version of liraglutide in June in the US, under a settlement agreement struck with Novo Nordisk in 2019
