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For example, a small number of subjects reported the following mild side effects in the course of a four-week glutathione study at the dose of 1g/day [13]: Flatulence Loose stools Flushing Weight gain In a more specialized study involving cystic fibrosis patients and much higher glutathione doses, some of the patients reported tightness in the torso, diarrhea, and fever-like symptoms [14]

Isolated tissue perfusion system Compared with isolated or/and culture cells, it is obviously more reasonable to separate the specific tissue where the metabolic enzymes are located for drugs metabolic research

found that TMAO induced mitochondrial dysfunction, thereby decreasing contractility of cardiomyocytes (100)