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Modern DDSsincluding lipid-based, polymeric, and stimuli-responsive platformshave demonstrated superiority over conventional therapies by optimizing pharmacokinetics, minimizing off-target effects, and enabling targeted delivery to pathological sites (e.g., renal tubules and inflamed joints)
Nat Immunol (2019) 20(9):11009
(2021) constructed iron-based metalorganic framework nanoparticles loaded with sorafenib and a peptide with tumor-penetrating properties, synergistically delaying HCC cell malignant transformation by stimulating ferroptosis
An interesting finding is that those who drank in moderation had a higher response to the vaccine than those who didnt drink alcohol at all
biophysica acta 1838 , 756765, (2014)