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Studies have highlighted the role of persistent fibrosis in aged tissues, where myofibroblasts in injured tissues of aged mice acquire a sustained senescent and apoptosisresistant phenotype, exacerbating fibrosis (Hecker et al ., 2014)
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The titration schemes cited here describe only the study protocols and are not instructions for action
New capillary networks formed through BPC-157-induced angiogenesis deliver oxygen-rich blood to hypoxic regions of the injured tendon, reversing the low-oxygen environment that otherwise delays cellular repair activity