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This study design gave the needed statistical analysis to trust the results

Mol Biol Evol 4, 406425 (1987)

3 Considering lab work thyroid, blood sugar/insulin, and hormone markers can reveal contributing factors that diet and medication alone wont fix

The clinical trials demonstrate that the vast majority of participants eventually achieve significant appetite suppression, but the timeline to get there varies by several weeks between individuals

For many people, the transition off the medication or to lower maintenance dosing is also important

Genetic PCA was used to capture the underlying population structure and define genetic ancestry more precisely, categorizing participants into groups such as European, South Asian, African, East Asian and other ancestries