does ghk-cu cause receptor downregulation or tolerance

does ghk-cu cause receptor downregulation or tolerance The delays aging in Caenorhabditis elegans via coordinated regulation of mitochondrial function and activation of DAF-16/SKN-1 pathways | Biogerontology GLP-1 Peptide VS Small Molecule!?!?

Name: does ghk-cu cause receptor downregulation or tolerance The delays aging in Caenorhabditis elegans via coordinated regulation of mitochondrial function and activation of DAF-16/SKN-1 pathways | Biogerontology GLP-1 Peptide VS Small Molecule!?!?
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Oligopeptide-2, also known as IGF-1 peptide, mimics insulin-like growth factor

Because of BPC-157s original gastric source, the oral version (as a mouth spray) is being used for GERD, stomach ulcers, Crohns disease, ulcerative colitis and leaky gut