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Like other GLP-1R agonists, when used alone or treated with non-insulin secretagogues, DUL treatment is associated with weight loss or decreased weight gain (107)

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Many patients lose more weight faster on semaglutide alone with a balanced diet than when combining GLP-1 therapy with strict keto dieting

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Nausea: Wegovy 2.4 mg: 44% (STEP 1) Zepbound 10 mg: 31% (SURMOUNT-1) Zepbound 15 mg: 36% (SURMOUNT-1) Tirzepatide produces modestly lower nausea rates at weight-loss-equivalent doses

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