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Future work should address the specific source of lipid peroxides in TME, the key molecules in driving lipid peroxidation to ferroptosis, as well as lipid peroxidation interdependence of immune cells and cancer cells in TME

Aroda VR, Edelstein SL, Goldberg RB, Knowler WC, Marcovina SM, Orchard TJ, et al

Periodic monitoring of serum B12 levels should be obtained to establish adequacy of therapy

These drugs include antifolates (methotrexate, 5-fluoruracil), anticonvulsants (Levodopa), hormone replacement medications, and lipid lowering drugs (fenofibrate or bezafibrate)

Combination with insulin requires insulin dose reduction (often significant) to prevent hypoglycemia

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