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Nature medicine 19, 576585 (2013)

In addition, the vaccine improved the physical activity of middle-aged mice (50 weeks old) and extended the median lifespan of ZMPSTE24 KO mouse (model of progeria), an extreme model of accelerated aging 62

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"If we treat addiction and compulsion and anhedonia, we cannot be ignoring a class of drugs that really directly acts in the reinforcement system," he said