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Zheng J, Xie Y, Ren L, Qi L, Wu L, Pan X, et al

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iGlarLixi does not require dose adjustment in patients with mild or moderate renal impairment, and post hoc data suggest that lixisenatide may reduce progression of renal complications, which may prove to be beneficial for the large proportion of older adults with T2D who have renal dysfunction and/or albuminuria

The findings of these studies combined clearly suggests that early management with GLP-1 receptor agonists may successfully prevent the development from simple steatosis to more serious liver disease

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Salehi et al 16 found that a GLP-1 antagonist prevented surges in GLP-1 and reduced hypoglycemic episodes in patients with PGBH