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A 2025 systematic review and meta-analysis of 12 studies (6,645 participants) confirmed significant correlations between klotho levels and cognitive function, supporting its potential as both biomarker and therapeutic target

doi: 10.3389/fimmu.2024.1380476 36 ChenYJinYStantonCRossRPZhaoJZhangHet al

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Detection of nitrotyrosine in aging and osteoarthritic cartilage: Correlation of oxidative damage with the presence of interleukin-1beta and with chondrocyte resistance to insulin-like growth factor 1

Bifidobacterium longum CCFM1077 attenuates hyperlipidemia by modulating the gut microbiota composition and fecal metabolites: a randomized, double-blind, placebo-controlled clinical trial

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