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Retatrutide is designed to bind to albumin, a protein that circulates in your blood
26 Step 7: Obtain pancreatic imaging If fasting hypoglycemia is present and hyperinsulinemic hypoglycemia is confirmed during a 72-hour fast, then pancreatic imaging should be obtained to evaluate for an insulinoma
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At the top dose, nausea affected 42.4% of people and vomiting affected 25.3%, with diarrhoea and constipation also more common than on placebo
Importantly, unlike monotherapy with pure glucagon agonists, retatrutide did not cause worsening of glycemic control the concurrent GLP-1 and GIP activity effectively offset any hyperglycemic tendency from glucagon receptor activation
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