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This function is especially important in erythrocytes, which lack mitochondria and therefore depend exclusively on the PPP for cytosolic NADPH

In arriving at our criteria we consulted three standard textbooks of medicine (Alstead, Davidson and Price), a consultant haematologist, the librarian at the Royal College of General Practitioners, and the Monthly Index of Medical Specialities

There is no evidence comparing the two

An ASO modified with LNA, ISTH0047, was designed to specifically decrease TGF-2 mRNA and protein, while sparing TGF-1 and TGF-3, demonstrating notable anticancer efficacy in preclinical animals

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