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A randomized, double-blind, placebo-controlled study to evaluate the effect of Erenumab on exercise time during a treadmill test in patients with stable angina

Researchers hope to determine whether the benefits observed in preclinical studies can be replicated in people living with type 2 diabetes or obesity

Dynamic treadmill exhaustion test and energy expenditure analysis were used to assess the severity of myopathy [69]

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The combined treatment downregulates the activity of the anti-apoptotic molecule Bcl-2, upregulates the expression of the pro-apoptotic molecules P53 and Bax, and increases the activity of caspases to promote endogenous apoptosis