Refrigeration requirements Compounded tirzepatide should be stored in the refrigerator at 36-46 degrees Fahrenheit (2-8 degrees Celsius)
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The tablet must be taken once daily in the morning on an empty stomach with a small amount of water, and at least 30 minutes must pass before eating, drinking, or taking other oral medications
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For instance, studies suggest that tirzepatide shows reduced -arrestin recruitment at GLP-1R, potentially reducing receptor desensitisation and enhancing tolerability
Most tirzepatide pens and vials maintain full potency for 28 days after first use when refrigerated correctly, though unopened medication typically remains stable for several months under these conditions