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Key Background Mounjaro was approved by the Food and Drug Administration in 2022, and Zepbound was approved in 2023

It is present at millimolar concentrations in every human cell, making it the most abundant intracellular antioxidant and the principal regulator of cellular redox state

[43] Thioridazine represents a critical example, as sertraline can increase thioridazine plasma levels, potentially leading to serious cardiac arrhythmias and QT interval prolongation