5.Do D, Lee T, Peasah SK, Good CB, Inneh A, Patel U
Differential vascularization, marrow composition, and osteocyte density between trabecular and cortical compartments likely modulate these divergent responses, collectively explaining the distinct patterns of bone loss observed under CR in mice
Why Microdosing GLP-1 Is Getting So Much Attention Microdosing GLP-1 is gaining attention as patients look for ways to reduce side effects, manage costs, or maintain results on lower doses
Current guidelines from the American Diabetes Association and surgical societies recommend individualized assessment of each patient's risk profile when determining the need for metformin discontinuation
But while the benefits of GLP-1 receptor agonists for the treatment of type 2 diabetes, obesity, and cardiovascular disease are well known, their impact on chronic kidney disease (CKD) has been less certain
GLP-1RAs, which are approved to treat type 2 diabetes, obesity, and obstructive sleep apnea, are now being investigated for their effects on processes involving appetite and satiety, reward processing, stress regulation, cognition, and neuroinflammation