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Consistently, the decline of SYP, PSD95, and BDNF protein occurred earlier and with greater severity in APP/PS1 mice compared to WT mice, indicating that ethanol exposure may cause more neuroinflammatory damage in APP/PS1 mice at molecular level

Homocysteine metabolism

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doi: 10.1016/j.ebiom.2020.102913

Major limitations include difficulties in maintaining the complex three-dimensional architecture of seminiferous tubules, establishing appropriate hormonal microenvironments, and sustaining long-term culture conditions necessary for the extended timeline of human spermatogenesis

Abstract Obesity is a chronic, relapsing disease driven by complex interactions between genetic, environmental, neuroendocrine and behavioural factors