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These pathways are active under stress-induced conditions [10, 19,20,21], suggesting that other pathways might provide neuroprotection under normal conditions

Thats not a reason to avoid it, but it is a reason to use it with a vet in the loop, start with conservative dosing, and monitor your dogs response throughout the protocol

In: Rose NR & Mackay IR ed

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CL Answer Can heat and humidity destroy whey protein and other sports nutrition supplements (e.g., creatine, BCAAs, digestive enzymes) during shipping or while storing at home