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Morbid obesity in PWS leads to increased risk of cardiopulmonary compromise, type 2 diabetes mellitus (DM), chronic leg edema, premature cardiovascular disease, and death [1,2]

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Dosage and cycle length depend on the specific peptide and individual goals

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If this is combined with long fasting intervals such as 16/8 or 5:2, the risk of insufficient energy and nutrient intake increases

Mechanism of Action Comparison# Semaglutide# Semaglutide is a selective GLP-1 receptor agonist -- a synthetic analog of human GLP-1(7-37) with two key structural modifications