This form of shedding is called telogen effluvium , and its typically triggered by significant physiological stressors, not by direct damage to the follicles themselves
In one published case, an active, lean-adjacent man lost about one-third of his total weight as muscle on 2.5 mg and recovered it after adding resistance training and increasing protein. This is a cautionary case, not an incidence estimate
10.1016/j.diabres.2025.112924 39 PanunziS.MalteseS.De GaetanoA.CapristoE.BornsteinS
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It's worth tracking for a week or two to confirm your own pattern
Usually, anyone with a body mass index (BMI) of 30 or higher can benefit from semaglutide or tirzepatide
