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They modulate genes crucial for lipid and glucose metabolism, thereby amplifying the insulin sensitivity of peripheral tissues

However, arginine may be beneficial in later stages of the disease, as it affects other metabolic functions [66]

Furthermore, slow-cycling tumour cells are addicted to glutamine-fuelled oxidative phosphorylation (OXPHOS) and rely on lipidome adaptations, particularly fatty acid oxidation pathways [17] for cell migration and invasion [18]