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There are theoretical concerns about the accelerated growth of pre-existing neoplasms due to the growth hormone pathway activity of Tesamorelin

However, one study found that headaches occurred slightly more often in people taking tirzepatide than the placebo: 9.4% of people taking Zepbound or Mounjaro reported headache, compared to 7.5% taking a placebo

The FDA is trying to catch knock-off drugs at the border with limited success

TABLE 1 Summary of methods used to identify GIPR expressing cells within the gastrointestinal tract

Obesity causes persistent fatigue through sleep apnea, chronic inflammation, insulin resistance, reduced cardiovascular capacity, and joint pain that limits activity

As proteins decompose, they release sulfur compounds, including hydrogen sulfide