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In the ATTAIN-1 trial, non-diabetic patients' weight loss was on average 12.4%

3, July 2006, pp

Zepbound is FDA-approved for weight loss

GLP-1 therapy has also shown benefit in improving atherothrombosis markers (e.g., inflammation, endothelial dysfunction, clotting in this population

It's everywhere right now

Illustrative GLP - 1 US adult adoption curve 10-year horizon 1 While usage for diabetes will continue to grow, the far larger growth driver will be users without a type 2 diabetes diagnosis who are focused on weight loss