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Psychiatry 11 , 354 (2021)

Clinicians should consider GLP-1 therapy when lifestyle modificationsincluding dietary changes and increased physical activityhave proven insufficient to achieve weight loss goals

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The proximity of these two mutations to the putative NADP-binding site of G6PD may contribute to the more severe form of disease (85)

Consistency matters more than optimization

GLP-1 receptor agonistsincluding semaglutide (Ozempic, Wegovy) and liraglutide (Victoza, Saxenda)along with tirzepatide (Mounjaro, Zepbound), a dual GIP/GLP-1 receptor agonist, have transformed the management of type 2 diabetes and obesity