semaglutide hepatotoxicity case report Liraglutide-Induced PDF) Semaglutide-associated drug-induced liver injury:

GLP-1R is widely distributed throughout the body, including the pancreas, central nervous system, gastrointestinal tract, cardiovascular system, and adipose tissue ( In our previous studies, we highlighted that abnormal lipid metabolism is closely associated with kidney allograft fibrosis, and we found CPT1A is a critical target in treatment of kidney allograft fibrosis ( To date, research on GLP-1R/GCGR agonists in the treatment of kidney fibrosis remains limited, and the effects of GLP-1R or GCGR agonists on kidney allograft fibrosis have not been investigated

Foretz et al., 2014

After an average follow-up of nearly a year, people taking GLP-1 drugs were 8% less likely to need a CPAP machine to help treat their sleep apnea, results showed

However, doctors noticed something interesting when patients started taking Ozempic for their diabetes: they were losing a significant amount of weight

Beware unintended consequences

One side effect is one too many