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GLP-1R and GIPR belong to class B1 of the G protein-coupled receptors, and share high homology and a similar action pattern

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With regular monitoring and gradual diabetes management, the risk of serious complications remains low

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The human colonic microflora is known to produce high concentrations of Short-Chain-Fatty acids (SCFAs), among other metabolites, from the anaerobic fermentation of dietary indigestible carbohydrates, or even derivatives of bile salts (389)