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Avoid rubbing the area afterwards

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If you become pregnant, please stop taking the medication and notify your Noom Med clinician immediately

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Timeline expectations: Weeks 1-4: Peak gas production as your body adjusts to medication Months 2-3: Gradual improvement for most users as digestive system adapts Month 6+: Significant reduction in symptoms, though some sensitivity may remain The silver lining: Most people find that gas issues dramatically improve after the initial adjustment period, and the weight loss benefits often outweigh the temporary digestive drama

The next day, sections were rinsed, incubated in secondary antibody in blocking solution for 2 h at room temperature on rotation and then rinsed and counterstained with Hoechst 33342 (1:2000 in PBS, Fisher #H3570) before being mounted on SuperFrost Plus slides (Fisher #12-550-15), dried and coverslipped with Prolong Gold Antifade mounting medium (Fisher #P36934)