The results showed that over 72 weeks, patients on the 10 mg dose lost an average of about 12.8% of their body weight, and those on the 15 mg dose lost an average of 14.7% of their body weight
Front Pharmacol 2018;9:913
Notably, Il1b was identified as a highly connected candidate gene, both in terms of its network degree and its well-documented role in metabolic and inflammatory regulation, suggesting it may play an important role in relevant signaling pathways
Retatrutide is an investigational triple receptor agonist that simultaneously activates GLP-1, GIP, and glucagon receptors to address multiple aspects of metabolic dysfunction
It works by mimicking a natural hormone called GLP-1 (glucagon-like peptide-1), which helps control blood sugar and reduces appetite
Eighteen months ago, she turned to tirzepatide, the active ingredient in GLP-1s like Mounjaro and Zepbound