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And when we connect biomarkers to actual disease burden, we make better, earlier decisions for patients while we wait for truly targeted Lp(a) therapies to arrive

However, he added that, in his opinion, a study comparing semaglutide with other meds to treat diabetes and heart failure would be helpful. Wright noted that [i]t now seems likely that cornerstone therapy for type 2 diabetic patients with obesity should be coadministration of an SGLT2 inhibitor and a GLP-1 receptor agonist, instead of the historic and perhaps now somewhat obsolete treatment with metformin and insulin. Whether their optimism is justified remains to be seen, but this study suggests that semaglutide could be an effective treatment for heart failure associated with diabetes.

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One study found that weight loss can reduce testosterone levels in women, which may lower sex drive especially in older women

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