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M., Trepp, R., Schmitt, A

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In infant populations, bottle-fed babies exhibit reduced fecal microbiota diversity and decreased numbers of beneficial bacteria such as Bifidobacterium and Parabacteroides [77]

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These endogenous gut hormones act on the central nervous system either via the circulation through areas deficient in the bloodbrain barrier, such as the median eminence of the hypothalamus and the area postrema [5] or via receptors of vagal afferents, together with stretch receptors and nutrient chemoreceptors [6]