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Compared with DPP-4 inhibitor users, those taking GLP-1RAs had a 13% lower risk of rheumatoid arthritis, 18% lower risk of gout and a modest reduction in osteoarthritis incidence over one year

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So it goes up to 1/2cc or 50 units

2A), warranting clinical studies

Your actual curve might be shifted slightly left or right, higher or lower