This assures that with enough data, such as that contained in MRFs, the average provides a more accurate estimate of the overall characteristic of the population being studied. Response: We recognize that the extent to which a sample statistic provides a reasonable representation of the population statistic depends, at least in part, on the sample size
Theyre used for treating iron deficiency anemia, vitamin B12 deficiency, electrolyte imbalances, pain, and as supportive therapy in critical and chronic disease care
doi.org/10.1016/j.molmed.2005.07.004 Bock-Marquette, I., et al
This combined therapy is especially useful for adults and elderly patients
Builds red blood cells Your body uses B12 to make new red blood cells and to produce hemoglobin, which is a protein that carries oxygen in your blood
Maintenance doses are typically 1 mg every 2-3 months for life High-dose oral therapy (1000-2000 micrograms daily) may be effective in selected patients with pernicious anaemia under clinical supervision, as passive diffusion can compensate for absent intrinsic factor, though this is not routine first-line treatment in the UK The water-soluble nature of B12 means that high-dose supplementation carries minimal risk of toxicity , making it a safe option for individuals with confirmed or suspected deficiency
